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Information about Compazine.
Take the missed dose as soon as you rememberSkip the missed dose if it is almost time for your next scheduled doseDo not take extra medicine to make up the missed dose.
Extrapyramidal reactions include acute dystoniaakathisiaparkinsonismand tardive dyskinesiaThese reactions have lasted months to yearsespecially in elderly patients with brain damage.
Many drugs can interact with CompazineNot all possible interactions are listed hereTell your doctor about all your current medicines and any you start or stop usingespecially:
Frequency not reportedConvulsiongrand mal/petit mal convulsionseizuresdizzinessaltered consciousnessextrapyramidal reactionsdystonia/acute dystonia/acute dystonic reactionsakinesiatardive dyskinesiaautonomic dysfunctionheadacheopisthotonoshyperreflexianeuroleptic malignant syndromecerebral edemaEEG changesaltered cerebrospinal fluid proteinsRef]
Acetylcholinesterase inhibitors may decrease the effectives of prochlorperazineCentrally acting acetylcholinesterase inhibitors may increase the neurotoxic effects of antipsychotic agentsCombining prochlorperazine with alcoholkava kavaCNS depressantsand cannabis may increase the risk of CNS depressant side effectsAntacids may decrease the absorption of prochlorperazineProchlorperazine may cause anticholinergic side effects such as dry mouthconstipationdry eyesdecreased urinary outputand mental confusionCombining agents with similar anticholinergic effects increases the risk of experiencing such adverse eventsProchlorperazine may increase the blood levels of dofetilideTikosynUse of both drugs is not recommendedDeferoxamineDesferalmay increase the risk of experiencing side effects of prochlorperazine treatmentCombination use has resulted in the prolonged loss of consciousnessMetoclopramideReglanmay increase the side effects of antipsychotic agentsCombination use is not recommendedProchlorperazine may increase the CNS depressant effects of orphenadrineNorflexor paraldehydeParalCombination use is not recommendedCombining prochlorperazine and potassium chloride may result in an increase in the ulcerogenic effect of potassium chlorideKlor-ConCombination use is generally not recommendedCombining prochlorperazine with thalidomideThalomidmay increase the risk of experiencing CNS depressant side effectsThis combination is generally not recommended.
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