Wellbutrin provides the same ingredients because zyban, a medication used to greatly help stop smoking.
Information about Zyban.
Take this medication by mouthusually twice daily with or without foodIf stomach upset occurstake with foodIt is important to take your doses at least 8 hours apart or as directed by your doctor to decrease your risk of seizure.
Zyban should be used with caution in older peopleGreater sensitivity in some older individuals cannot be ruled outThe recommended dose in older people is 150mg once a daysee section 4.4
But varenicline also limits the effect of inhaled nicotine on these receptors tooSo if someone taking the medicine does smokethe nicotine inhaled will have little to no effect on receptors in the brainrendering the act of smoking chemically impotentThis consequently makes the act of smoking less desirable.
Patients with hepatic impairmentBupropion is extensively metabolised in the liver to active metaboliteswhich are further metabolisedNo statistically significant differences in the pharmacokinetics of bupropion were observed in patients with mild to moderate hepatic cirrhosis compared with healthy volunteersbut bupropion plasma levels showed a higher variability between individual patientsTherefore Zyban should be used with caution in patients with mild to moderate hepatic impairment and 150 mg once a day is the recommended dose in these patients.
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details of interactions are in the zyban data sheet which is on the medsafe web site www.